• Users Online: 81
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2021  |  Volume : 21  |  Issue : 4  |  Page : 194-202

The burden of diabetic kidney disease in Nigeria − systematic review and meta-analysis

1 Endocrinology Unit, Department of Medicine, University College Hospital, Ibadan; Oluwafemi EFUNTOYE (MBBS, FWACP), Alliance Hospital, Abuja, Nigeria
2 Oluwafemi EFUNTOYE (MBBS, FWACP), Alliance Hospital, Abuja, Nigeria
3 Zenith Medical and Kidney Centre, Alliance Hospital, Abuja, Nigeria
4 Department of Medicine, University College Hospital, Ibadan, Nigeria
5 College of Medicine, University of Ibadan, Ibadan, Nigeria

Correspondence Address:
Dr. Taoreed A Azeez
Endocrinology Unit, Department of Medicine, University College Hospital, Ibadan, Postal/Zip Code: 23402
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jesnt.jesnt_16_21

Rights and Permissions

Background Diabetic kidney disease (DKD) is a microvascular complication of diabetes mellitus. Considering that the burden of diabetes mellitus is rising in Nigeria, there is a need to ascertain the burden of one of its most common complications. The objective of the meta-analysis was to determine the pooled prevalence of DKD in Nigeria and identify its risk factors. Patients and methods The study is a meta-analysis and it followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Google scholar, PubMed, AJOL, SCOPUS, medRxiv, and the gray literature were systematically searched using appropriate key terms. Statistical analysis was done with MetaXL. The inverse-variance heterogeneity model was used for the meta-analysis and heterogeneity was determined using the I2 statistic and the Cochran’s Q test. Publication bias was checked with the Doi plot and LFK index. Results Nineteen studies met the eligibility criteria. The total sample size was 56 571. The pooled prevalence of DKD in Nigeria was 28% (95% confidence interval 3–58). The Cochran’s Q was 747 (P<0.001), while the I2 statistic was 97.6%. The Doi plot was drawn and the LFK index was 6.22. The most common risk factors for DKD were suboptimal glycemic control, hypertension, obesity, duration of diabetes, male sex, and advancing age. Conclusion The prevalence of DKD in Nigeria is high and greater attention should be focused on managing the risk factors so as to alleviate the burden of the disease.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded73    
    Comments [Add]    
    Cited by others 1    

Recommend this journal